Sucker Punch's Brian Fleming has posted some more information on the Karma System for InFamous 2 over on the US PS Blog.
According to Flemming, when thinking about what the team wanted to do to improve the Karma System for the sequel, the team decided to make the choices clearer and more believable while also making it about the players' relationships and less about a specific choice.
"So instead of a question that really didn’t relate to our primary gameplay (e.g. “should we take this food or give it away?”), in InFamous 2 we let the player decide who to ally with on a quest, or choose between Kuo’s surgical strike or Nix’s no-holds barred assault," he wrote. "You aren’t just choosing a mission, you’re choosing an ally and alienating another person. This was both clear for players, and more real."
A couple of videos related to the Karma System were also posted, and you can watch both below.
InFamous 2 is out on PS3 thus year.