According to a LinkedIn help wanted posting from Visceral Games, Dead Space 2 is currently in pre-production.
Here's some information pulled from it:
This M-rated action/shooter sequel will set new standards for an action-packed story-driven console experience.
The game is in the later stages of pre-production, ready for production in the next few months, with many of the navigational and combat mechanics in place. We have complete autonomy and creative control over our own decisions. The Games Label at EA is 100% committed to this IP, and has already worked on IP extensions such as comic, animated features, and action figures.
The ad was spotted by Superannuation.