According to PGN, Lords of Shadow 2, which'll also come to PS3 and Xbox 360, will interact with 3DS spin-off Mirror of Fate. The 3DS game will apparently use 3DS's forward-facing camera as a mirror, while the outward camera will help solve puzzles.
Mirror of Fate was also apparently in development for Wii U, but was tossed out for Lords of Shadow 2 instead. The Wii U version of MoF would have been similar to the 3DS SKU.
Both games are in development at MercurySteam, which launched the original Lords of Shadow in 2010 in collaboration with Kojima Productions.