French gaming magazine Joystick has the sequel to Prey on its next cover. Yes, that would be Prey 2.
3D Realms' Scott Miller confirmed the sequel to Prey back in 2008, with his management company Radar Group, 2K and Human Head Studios behind it.
It was pegged for a PC and Xbox 360 release upon announcement, but rights to the franchise have since been purchased by Zenimax, meaning it will likely be published by Bethesda.
Expect more on this soon, we reckon.