Bioware's Chris Priestly has confirmed on the firm's forum that Mass Effect 3 on PC will, as suspected, require Origin and will not "initially" be made available on Steam.
"Origin is required for all PC editions of Mass Effect 3, physical or digital," wrote Priestly in a post regarding frequently asked questions. "Mass Effect 3 will require a one time, single authorization for the single player game. There is no limit to the number of installs. Playing Mass Effect 3 Multiplayer will require a constant connection."
He goes on to say that during the game's "initial release" it will be made available through other digital PC retailers, but not on Steam due to "a set of restrictive terms of service which limit how developers interact with customers to deliver patches and other downloadable content."
"We are intent on providing Mass Effect to players with the best possible experience no matter where they purchase or play their game, and are happy to partner with any download service that does not restrict our ability to connect directly with our consumers," said Priestly.
Obvious news, but still something you should be made aware of.
Mass Effect 3 launches on March 6 in North America and March 9 in Europe.