Rumors of Bane being present in Batman: Arkham City have been making the rounds for a while now, and thanks to the latest issue of the Arkham City comic book series, the possibility is looking more likely.
According to Issue #5: "Inside Arkham City, entrapped criminals have to find new ways to keep themselves occupied. In Bane's case, he's biding his time by running an extreme fighting ring. The lack of serious competition leaves him frustrated, until an otherwise lacklustre opponent produces a big surprise. The result may inspire Bane to take on deadlier hobbies."
ArkhamcityUK also has some interesting information posted regarding the Titan serum, how it relates to Bane, and how the Joker came to be in possession of it. We'll let you look at the rest in case it is spoileriffic.
We'll ask Warner about Bane just to be sure.
Batman: Akrham City launches on October 18 in the US and October 21 in the UK.