Well, potentially. Amazon US’s Mass Effect 2 product page appears to have some basic plot details of the upcoming BioWare sequel. And they are:
The second chapter in the Mass Effect trilogy takes you to the darkest reaches of space, where you must uncover the mystery behind the disappearance of humans across many worlds. Prepare yourself for a suicide mission to save mankind. Travel the galaxy to assemble a team of soldiers and combat specialists, and launch an all-out assault on the heart of enemy territory.
Expect to hear more on the game at GDC this week.
Thanks, Kotaku and Blerk.