"You can't really complain about grinding if you're a trophy whore." I don't see why not.
I have a feeling we won't see eye to eye on this, BUT, I'm gonna give it a shot. :)
First of all, I use the word "grinding" to mean "non-fun, repetitive actions". If grinding's the wrong word, then someone please steer me right. Anyway, you tell me to go find bobbleheads, or kill all of the behemoths, I'm in. You tell me to break my legs 20 times, fuck that. Why? Because it's boring and not fun.
Before there were trophies I was a completionist, which probably describes me a bit better. I found every piece of heart in Zelda, I cleared every stage in SuperMarioWorld, and I saw the proper ending of Metroid Prime. I like a challenge too, so I general play the more difficult levels of the game too, but I'll be the first to admit that the OCD in me drives me to complete even the non-fun trophies just for the sake of completion.
However, I would argue that everyone plays shit they don't enjoy. You don't get to a stage you don't like and say "I quit this game forever!", everyone is prepared to put up with a bit of shit to at least finish the game. For me, finishing the game means platinuming it.
I should also add that it's not just that, the New Vegas story wasn't as epic as F3 for me. And it was mostly more of the same. Also, some of the new things which I liked in theory (the factions and the hardcore mode) turned out to be just a hassle.
Anyway, that's how I see it. There were a lot of good in New Vegas, I recognise that, and some great missions. But I never really had that feeling I had saving DC and hearing about my exploits on the radio, and finding other vaults with crazy shit going on, and that first time I saw a Deathclaw peggin' it towards me, and learning how to wear power armor, and all that good shit... I dunno, nostalgia maybe?